ABSTRACT
Aim: We describe a 52 year old gentleman who had a third ventricular lesion, presumed to be epidermoid cyst, which is very rare. We also describe the appearances of this rare condition on newer MRI sequences. Presentation of Case: Third ventricle is a rare site of epidermoid cysts and difficult to visualise specially in routine MRI sequences. We used 3D FLAIR sequence as part of routine MRI protocol that was helpful in raising suspicion initially, aided by clinical presentation. Subsequent 3D T2 SPACE sequence confirmed the presence of abnormality. Discussion: The case highlights the importance of high resolution 3D FLAIR sequence as part of initial MRI protocol that is devoid of CSF flow artefacts and therefore helpful for small intraventricular lesions. Importance of 3D T2 SPACE is also highlighted which is another new MRI sequence. It has excellent spatial resolution without artefacts that is helpful in clearly delineating the presence of small lesions such as epidermoid cyst and its relationship with surrounding structures and increasing diagnostic certainty. Conclusion: We present a rare case of presumed third ventricular epidermoid cyst and potential role of newer MRI sequences in small intraventricular lesions.